AIC Renal Biota Care is a targeted, high-potency probiotic formulation designed to support the gut-kidney axis through a combination of 9 selected probiotic strains providing 100 Billion CFU. It focuses on oxalate metabolism, endotoxin load, phosphorus metabolism, uremic toxin reduction, and renal inflammation, treating the gut as the main cause of the advancement of chronic kidney disease.

Key Benefits
• Supports the Gut-Kidney Axis – Helps maintain a healthier relationship between intestinal microbiota, gut barrier function, and renal health.
• Supports Healthy Uremic Toxin Metabolism – Targets gut microbial pathways involved in the production and metabolism of compounds such as indoxyl sulfate and p-cresol sulfate.
• Supports Gut Barrier Integrity – Helps maintain intestinal barrier function and may help reduce unwanted translocation of microbial-derived compounds.
• Supports Oxalate Metabolism – Selected Lactobacillus strains support healthy intestinal oxalate handling.
• Supports Butyrate & SCFA Production – Provides strains associated with beneficial short-chain fatty acid production and intestinal health.
• Supports Digestive & Immune Balance – Helps maintain microbial diversity, digestive regularity, and healthy gut-immune signalling.
• Supports Healthy Renal Inflammatory Balance – Helps support pathways associated with maintaining a healthy inflammatory response in the kidneys.
• Supports Mood & Stress Balance in CKD – Helps support the gut-brain axis and healthy mood and stress regulation in individuals with CKD.
 
Key Ingredients
 
• Bifidobacterium longum (25 Billion CFU): Supports a balanced intestinal microbiome and gut barrier function. May support healthy metabolism of gut-derived compounds such as indoxyl sulfate and p-cresol.
• Bifidobacterium bifidum (15 Billion CFU): Supports beneficial gut bacteria, mucosal health, and immune balance. May help maintain a healthy intestinal environment and microbial balance.
• Lactobacillus plantarum (20 Billion CFU): Supports healthy intestinal oxalate handling and microbial balance. May support a healthy inflammatory response and metabolic health.
• Lactobacillus acidophilus (10 Billion CFU): Supports digestive health, microbial balance, and normal intestinal function. May support healthy digestion and metabolism of nitrogenous compounds.
• Pediococcus acidilactici (10 Billion CFU): Supports beneficial microbial balance and healthy digestive function. May help maintain a healthy intestinal environment and microbial composition.
• Bacillus coagulans (10 Billion CFU): Supports digestive health, microbial balance, and normal bowel regularity. May support a healthy intestinal inflammatory balance.
• Clostridium butyricum (5 Billion CFU): Supports butyrate and short-chain fatty acid production. Helps maintain intestinal health and a healthy gut barrier.
• Lactococcus lactis (5 Billion CFU): Supports beneficial microbial activity and intestinal barrier function. May contribute to healthy SCFA production and maintenance of intestinal tight-junction integrity.
• Pasteurized Akkermansia muciniphila (10 mg): Supports the intestinal mucin layer and gut barrier function. May help maintain healthy metabolic and glucose regulation.
 
Key Indications
 
Useful for individuals with:
• Chronic Kidney Disease (CKD) – As adjunctive gut microbiome support under practitioner supervision.
• Gut Dysbiosis Associated With CKD – Supports maintenance of a balanced intestinal microbiome.
• Elevated Gut-Derived Uremic Toxin Burden – Supports healthy gut microbial pathways involved in uremic toxin metabolism.
• High Urinary Oxalate / History of Calcium Oxalate Kidney Stones – Supports healthy intestinal oxalate handling and metabolism.
• Intestinal Permeability / Gut Barrier Dysfunction – Supports intestinal barrier integrity and healthy gut permeability.
• Chronic Constipation or Irregular Bowel Movements – Supports digestive regularity and normal bowel function.
• CKD-Associated Digestive Discomfort – Supports digestive health and overall intestinal function.
• Renal Inflammatory Patterns – Supports a healthy inflammatory balance associated with kidney health.
• Oxalate-Related Gut or Metabolic Concerns – Supports healthy oxalate metabolism and intestinal microbial balance.
• Dialysis or Pre-Dialysis Patients – As adjunctive gut microbiome support under the guidance of a qualified healthcare practitioner.
 
Frequently Asked Questions
1-What is the gut-kidney axis?
The gut-kidney axis describes the two-way relationship between the intestinal microbiome, gut barrier, and kidney function. In CKD, changes in the gut microbiome may contribute to increased production and accumulation of gut-derived uremic toxins and inflammatory compounds.
 
2-How can probiotics support kidney health?
Certain probiotics may influence gut microbial composition and the production or metabolism of gut-derived compounds. Clinical studies have investigated probiotics and synbiotics for their effects on markers such as BUN and uremic toxins. Results vary, and probiotics should be considered adjunctive support rather than a treatment for CKD.
 
3-Is Renal Biota Care safe for dialysis patients?
Renal Biota Care may be used as adjunctive gut health support alongside dialysis under nephrologist supervision. It is not a replacement for dialysis or prescribed renal medications. Discuss use with your nephrologist before starting, particularly regarding individual dietary requirements and potassium and phosphorus monitoring.
 
4-Can Renal Biota Care be taken with CKD medications?
Because CKD patients may be taking multiple medications, supplements should be reviewed with the treating nephrologist or healthcare professional before use. This is particularly important for patients with advanced CKD, those undergoing dialysis, or kidney transplant recipients.
 
5-How is this different from a regular probiotic?
A regular probiotic is generally formulated for broad digestive and gut health. Renal Biota Care is formulated with the gut-kidney axis in mind, with strains selected based on research investigating their potential roles in gut microbial balance, uremic toxin metabolism, intestinal barrier function, oxalate metabolism, and inflammatory balance. It is intended as targeted adjunctive support rather than a general-purpose probiotic.
 
6-How long before I see results?
Individual responses can vary. Improvements in bowel regularity and digestive comfort may be noticed within a few weeks, while changes in gut microbiome-related or biochemical markers may require longer-term, consistent use. Clinical outcomes vary between individuals and should be assessed with appropriate healthcare monitoring.
 
7-Can practitioners recommend Renal Biota Care?
Yes. Renal Biota Care is designed for practitioner-guided use as part of a comprehensive CKD management approach. It should complement, not replace, established clinical care, which may include dietary management, medication, dialysis when indicated, and regular monitoring of renal function and relevant laboratory markers.